Article

Development of novel <i>in vitro</i> human alveolar epithelial cell models to study distal lung biology and disease

2020-12-26

Abstract excerpt

<h4>ABSTRACT</h4> Many acute and chronic lung diseases affect the distal lung alveoli. Although airway-derived human cell lines exist, alveolar epithelial cell (AEC)-derived lines are needed to better model these diseases. We have generated and characterized novel immortalized cell lines derived from human AECs. They grow as epithelial monolayers expressing lung progenitor markers SOX9 and SOX2, with little to no...

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Literature Corpus work: c3cec8f9-b82d-5ccd-a55d-7e6459545847
DOI: 10.1101/2020.12.25.424415

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