Article

A spatially-resolved blueprint of the developing human lung reveals a WNT-driven niche for basal stem cells

2024-10-03

Abstract excerpt

<h4>ABSTRACT</h4> Organs are composed of diverse cell types that change across space and time during development. To interrogate this diversity, we micro-dissected developing human lungs along the proximal-distal axis during the late pseudoglandular stage and generated an integrated analysis of single-nucleus sequencing and spatial transcriptomics, creating a cellularly-resolved atlas of the lung. These rich data...

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Literature Corpus work: 4131d22e-3baf-5057-ad6e-475c9405ac9c
DOI: 10.1101/2024.10.01.612096

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