An update in club cell biology and its potential relevance to chronic obstructive pulmonary disease

Abstract excerpt

Club cells are found in human small airways where they play an important role in immune defense, xenobiotic metabolism, and repair after injury. Over the past few years, data from single-cell RNA sequencing (scRNA-seq) studies has generated new insights into club cell heterogeneity and function. In this review, we integrate findings from scRNA-seq experiments with earlier in vitro, in vivo, and microscopy studies...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Congenital Diaphragmatic Hernia Studies
• Share to Neonatal Respiratory Health Research
• Share to Tracheal and airway disorders