Article

ARF4-mediated Retrograde Trafficking Drives Chemoresistance in Glioblastoma

2021-07-19

Abstract excerpt

<h4>ABSTRACT</h4> Glioblastoma (GBM) is the most common type of adult malignant brain tumor, with a median survival of only 21 months. This is partly due to the high rate of resistance to conventional therapy, including temozolomide (TMZ), leading to recurrence rates close to 100%. It still remains unknown what drives the development of this resistance. To identify the unknown genes driving the development of thi...

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Literature Corpus work: d38cea2c-5e05-5cf9-9f12-19b8febe857e
DOI: 10.1101/2021.07.18.451328

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