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Unlocking Glioblastoma Vulnerabilities with CRISPR-Based Genetic Screening

23 May 2024

Abstract excerpt

Glioblastoma (GBM) is the most common malignant brain tumor in adults. Despite advancements in treatment, the prognosis for patients with GBM remains poor due to its aggressive nature and resistance to therapy. CRISPR-based genetic screening has emerged as a powerful tool for identifying genes crucial for tumor progression and treatment resistance, offering promising targets for tumor therapy. In this review, we...

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PMID: 38891890
DOI: 10.3390/ijms25115702

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