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Article

ARF4-mediated retrograde trafficking as a driver of chemoresistance in glioblastoma

19 Mar 2024

Abstract excerpt

BACKGROUND: Cellular functions hinge on the meticulous orchestration of protein transport, both spatially and temporally. Central to this process is retrograde trafficking, responsible for targeting proteins to the nucleus. Despite its link to many diseases, the implications of retrograde trafficking in glioblastoma (GBM) are still unclear. METHODS: To identify genetic drivers of TMZ resistance, we conducted...

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PMID: 38506351
DOI: 10.1093/neuonc/noae059

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