Article

A Conditional Cas9 System for Stage-Specific Gene Editing in <i>P. falciparum</i>

2025-03-11

Abstract excerpt

The malaria parasite has a complex lifecycle involving various host cell environments in both human and mosquito hosts. The parasite must tightly regulate gene expression at each stage in order to adapt to its current environment while continuing development. However, it is challenging to study gene function and regulation of essential genes across the parasite’s multi-host lifecycle. Thus, we adapted a recently d...

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Literature Corpus work: d3754bdc-fa22-52d9-b7e8-41895e1c0402
DOI: 10.1101/2025.03.09.642268

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