Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Leak-Free Inducible CRISPRi/a System for Gene Functional Studies in Plasmodium falciparum

5 May 2022

Abstract excerpt

. We evaluated the robustness and versatility of this system by activating or repressing eight selected genes and achieved up- and downregulation of the targeted genes located in both the euchromatin and heterochromatin regions. This system offers the malaria research community another tool for functional genetic studies.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Malaria Research and Control
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35510853
DOI: 10.1128/spectrum.02782-21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Leak-Free Inducible CRISPRi/a System for Gene Functional Studies in Plasmodium falciparumPMID 35510853Read ↗

Efficient Editing of Malaria Parasite Genome Using the CRISPR/Cas9 SystemSemantic proximity Read ↗

CRISPR/Cas9 gene editing to make conditional mutants of the human malaria parasite <i>Plasmodium falciparum</i>Semantic proximity Read ↗

Ribozyme-Mediated, Multiplex CRISPR Gene Editing and CRISPRi in <i>Plasmodium yoelii</i>Semantic proximity Read ↗

A Conditional Cas9 System for Stage-Specific Gene Editing in <i>P. falciparum</i>Semantic proximity Read ↗

Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 systemSemantic proximity Read ↗

CRISPR-mediated genome editing of Plasmodium falciparum malaria parasitesSemantic proximity Read ↗

CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impactSemantic proximity Read ↗

Cutting back malaria: CRISPR/Cas9 genome editing of PlasmodiumSemantic proximity Read ↗

CRISPR-Cas13 in malaria parasite: Diagnosis and prospective gene function identificationSemantic proximity Read ↗

Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite DevelopmentSemantic proximity Read ↗

CRISPR/Cas9 Gene Editing to Make Conditional Mutants of Human Malaria Parasite P. falciparumSemantic proximity Read ↗

Improvement of CRISPR/Cas9 system by transfecting Cas9-expressing Plasmodium berghei with linear donor templateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.