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Efficient Editing of Malaria Parasite Genome Using the CRISPR/Cas9 System

2 Jul 2014

Abstract excerpt

Malaria parasites are unicellular organisms residing inside the red blood cells, and current methods for editing the parasite genes have been inefficient. The CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats and Cas9 endonuclease-mediated genome editing) system is a new powerful technique for genome editing and has been widely employed to study gene function in various organisms. However,...

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PMID: 24987097
DOI: 10.1128/mbio.01414-14

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