Article

Differential requirement for IRGM proteins during tuberculosis infection in mice

2022-11-09

Abstract excerpt

<h4>ABSTRACT</h4> Mycobacterium tuberculosis ( Mtb ) is a bacterium that exclusively resides in human hosts and remains a dominant cause of morbidity and mortality among infectious diseases worldwide. Host protection against Mtb infection is dependent on the function of immunity-related GTPase clade M (IRGM) proteins. Polymorphisms in human IRGM associate with altered susceptibility to mycobacterial disease, a...

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Literature Corpus work: d351fe95-5f3c-515d-8403-6fcd811f2191
DOI: 10.1101/2022.11.09.515519

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