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Polygenic scores for tobacco use provide insights into systemic health risks in a diverse EHR-linked biobank in Los Angeles

2023-03-17

Abstract excerpt

<title>Abstract</title> <p>Tobacco use is a major risk factor for multiple diseases and is heavily influenced by environmental factors with significant underlying genetic contributions. Here, we evaluated the predictive performance, risk stratification, and potential systemic health effects of tobacco use disorder (TUD) predisposing germline variants using a European- ancestry derived polygenic score (PGS) in 24,...

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Literature Corpus work
d30941b9-63bf-5d1e-bc46-03885c3c4221
DOI
10.21203/rs.3.rs-2645173/v1
Open publication

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Polygenic scores for tobacco use provide insights into systemic health risks in a diverse EHR-linked biobank in Los AngelesDOI 10.21203/rs.3.rs-2645173/v1
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