Article

Isostere <sup>18</sup> F-protein post-translational editing enables dynamic tracking of neurodegeneration biomarkers

2025-01-26

Abstract excerpt

The neurofilament light chain protein (NfL) is a suggested general marker for neuronal loss. Its release from brain parenchyma into cerebral spinal fluid, and presumed detection in blood has seen it established as a first blood-based marker of disease activity and drug efficacy in multiple sclerosis (MS) and in the presymptomatic diagnosis and assessment of disease course for other neurodegenerative disorders. 1...

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Literature Corpus work: d2e9c6ad-2a74-5c36-b800-1e28878e7bbd
DOI: 10.1101/2025.01.26.634877

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