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Cell Settling, Migration, and Stochastic Cancer Expression Suggest Potassium Flux Per H <sup>+</sup> - Sensitive KCN Members Associated with Oncogenes and Histone/DNA Modulators Potentially Initiates pH-Reversal

2025-07-03

Abstract excerpt

<h4>ABSTRACT</h4> Attraction of glioblastoma cells to potassium was suspected when cells clustered around dying cells and they migrated towards serum (high [K + ]) and a positive potassium gradient. Potassium channel proteins (KCN family, 90 members) mediating altered transmembrane flux may provide K + that releases H + bound to inner membranes in cancer cells for cytosolic proton transfer (possibly Grotthuss)...

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Literature Corpus work
d2e30744-bdfb-5262-ac57-598d387b5abb
DOI
10.1101/2025.06.29.662144
Open publication

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Cell Settling, Migration, and Stochastic Cancer Expression Suggest Potassium Flux Per H <sup>+</sup> - Sensitive KCN Members Associated with Oncogenes and Histone/DNA Modulators Potentially Initiates pH-ReversalDOI 10.1101/2025.06.29.662144
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