Article

Parental kynurenine 3-monooxygenase genotype in mice directs sex-specific behavioral outcomes in offspring

2024-12-20

Abstract excerpt

<h4>Background: </h4> Disruptions in brain development can impact behavioral traits and increase the risk of neurodevelopmental conditions such as autism spectrum disorder, attention-deficit/hyperactivity disorder (ADHD), schizophrenia, and bipolar disorder, often in sex-specific ways. Dysregulation of the kynurenine pathway (KP) of tryptophan metabolism has been implicated in cognitive and neurodevelopmental diso...

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Literature Corpus work: d2bef7d2-1df0-5b57-8677-d8faf8299de9
DOI: 10.1101/2024.12.18.629210

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