Article

Hypothalamic-pituitary-adrenal axis dysfunction worsens epilepsy outcomes and increases SUDEP risk

2022-03-17

Abstract excerpt

<h4>Summary</h4> Epilepsy is often comorbid with psychiatric illnesses, including anxiety and depression. Despite the high incidence of psychiatric comorbidities in people with epilepsy, few studies address the underlying mechanisms. Stress can trigger both epilepsy and depression and significant accumulating evidence, from both human and animal studies, support that hypothalamic-pituitary-adrenal (HPA) axis dysf...

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Literature Corpus work: 3aa8e9f4-903f-599f-b8ce-a57fe8f837e3
DOI: 10.1101/2022.03.15.484525

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