Article

Single cell transcriptome mapping identifies a local innate B cell population driving local antibody production and chronic rejection after lung transplantation

2021-02-17

Abstract excerpt

Bronchiolitis obliterans syndrome (BOS) due to chronic rejection is the main reason for poor outcomes after lung transplantation (LTx). We and others have recently identified B cells as major contributors to BOS after LTx. The extent of B cell heterogeneity, however, as well as those B cell populations that determine chronic rejection of the lung, remain entirely unclear. Here, we provide a map of cell population...

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Literature Corpus work: d23906a9-8789-5768-9553-78a3bafa0d9c
DOI: 10.1101/2021.02.16.431278

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