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Single-cell and spatial transcriptomics resolve airway obliteration in bronchiolitis obliterans syndrome

2026-08-23

Abstract excerpt

<h4>Background: </h4> Chronic lung allograft dysfunction (CLAD) is the leading cause of death beyond the first year after lung transplantation, and its most frequent phenotype is bronchiolitis obliterans syndrome (BOS), a fibrotic small-airway disease. Mechanistic work has focused on the immune compartment, yet intensified immunosuppression does not alter established disease. <h4>Aim:</h4> To resolve which structu...

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Literature Corpus work
cf438ffd-11ed-5e92-80a9-8b024092b719
DOI
10.64898/2026.08.21.746071
Open publication

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Single-cell and spatial transcriptomics resolve airway obliteration in bronchiolitis obliterans syndromeDOI 10.64898/2026.08.21.746071
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