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Article

Genome dynamics in Legionella: the basis of versatility and adaptation to intracellular replication.

Cold Spring Harbor perspectives in medicine - 1 Jun 2013

Gomez-Valero Laura, Buchrieser Carmen

Abstract excerpt

Legionella pneumophila is a bacterial pathogen present in aquatic environments that can cause a severe pneumonia called Legionnaires' disease. Soon after its recognition, it was shown that Legionella replicates inside amoeba, suggesting that bacteria replicating in environmental protozoa are able to exploit conserved signaling pathways in human phagocytic cells. Comparative, evolutionary, and functional genomics...

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Identifiers

PMID: 23732852
DOI: 10.1101/cshperspect.a009993
PMCID: PMC3662349

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