Back to search

Article

Transposon-insertion sequencing in a clinical isolate of <i>Legionella pneumophila</i> identifies essential genes and determinants of natural transformation

2020-10-04

Abstract excerpt

Legionella pneumophila is a Gram-negative bacterium ubiquitous in freshwater environments which, if inhaled, can cause a severe pneumonia in humans. The emergence of L. pneumophila is linked to several traits selected in the environment, the acquisition of some of which involved intra- and interkingdown horizontal gene transfer events. Transposon-insertion sequencing (TIS) is a powerful method to identify the gen...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
50f63c60-3adc-5319-8d6a-6fc15a57dc1d
DOI
10.1101/2020.10.01.323287
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Transposon-insertion sequencing in a clinical isolate of <i>Legionella pneumophila</i> identifies essential genes and determinants of natural transformationDOI 10.1101/2020.10.01.323287
Transposon mutagenesis screen in <i>Klebsiella pneumoniae</i> identifies genetic determinants required for growth in human urine and serumSemantic proximity
Identification of genes required for long term survival of <i>L. pneumophila</i> in waterSemantic proximity
Identifying essential genes in Mycobacterium tuberculosis by global phenotypic profiling.Semantic proximity
<i>Legionella pneumophila</i> CRISPR-Cas suggests recurrent encounters with <i>Gokushovirinae</i>Semantic proximity
Identification of Genes Required for Long-Term Survival of Legionella pneumophila in Water.Semantic proximity
Expansion, restructuring and characterization of the <i>Legionellaceae</i> familySemantic proximity
Genome-Wide Saturation Mutagenesis of Burkholderia pseudomallei K96243 Predicts Essential Genes and Novel Targets for Antimicrobial DevelopmentSemantic proximity
Pangenome evaluation of gene essentiality in <i>Streptococcus pyogenes</i>Semantic proximity
Random barcode transposon-site sequencing in <i>Mycobacterium tuberculosis</i> reveals the functions of uncharacterized genesSemantic proximity
Massively parallel mutant selection identifies genetic determinants of <i>Pseudomonas aeruginosa</i> colonization of <i>Drosophila melanogaster</i>Semantic proximity
Transposon insertion site sequencing (TIS) of Pseudomonas aeruginosa.Semantic proximity
DNA binding is rate-limiting for natural transformationSemantic proximity
Select a neighboring publication to make it the new centre.