Article

Bone marrow lymphocyte dynamics during chemotherapy in pediatric acute myeloid leukemia

2025-05-09

Abstract excerpt

<h4>SUMMARY</h4> A better understanding of lymphocyte dynamics during current treatment regimens in pediatric AML is urgently needed to understand whether the application of bispecific T-cell-engagers (BiTEs) during periods of low tumor burden could be a viable treatment strategy. In this study, we found that induction 1, comprising mitoxantrone-etoposide-cytarabine in nearly all patients (as part of the NOPHO-DB...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d1c39783-cca1-524a-8938-390d24fc8983
DOI: 10.1101/2025.05.04.652110

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bone marrow lymphocyte dynamics during chemotherapy in pediatric acute myeloid leukemiaDOI 10.1101/2025.05.04.652110Read

How to drug a leukemic stem cell: deciphering heterogeneity for better specificitySemantic proximity Read

A multiomic atlas identifies a treatment-resistant, bone marrow progenitor-like cell population in T cell acute lymphoblastic leukemia.Semantic proximity Read

Therapeutic targeting of acute myeloid leukemia stem cellsSemantic proximity Read

A longitudinal single-cell atlas of treatment response in pediatric AMLSemantic proximity Read

Mining single-cell transcriptomic data reveals distinct T-cell population in pediatric B-ALL and AML at diagnosisSemantic proximity Read

Longitudinal single-cell analysis reveals treatment-resistant stem and mast cells with potential treatments for pediatric AML.Semantic proximity Read

Opportunities for immunotherapy in childhood acute myeloid leukemia.Semantic proximity Read

Acute Myeloid Leukemia Evolving from Myeloproliferative Neoplasms: Many Sides of a Challenging DiseaseSemantic proximity Read

Identification and targeting of treatment resistant progenitor populations in T-cell Acute Lymphoblastic LeukemiaSemantic proximity Read

Functional diversification and dynamics of CAR-T cells in patients with B-ALLSemantic proximity Read

Immunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CMLSemantic proximity Read

Post-stem cell transplant maintenance for pediatric acute leukemias: insights from a Brazilian institution with a Latin American perspectiveSemantic proximity Read