Article

Identification and targeting of treatment resistant progenitor populations in T-cell Acute Lymphoblastic Leukemia

2023-10-30

Abstract excerpt

<title>Abstract</title> <p>Refractoriness to initial chemotherapy and relapse after remission are the main obstacles to cure in T-cell Acute Lymphoblastic Leukemia (T-ALL). Biomarker guided risk stratification and targeted therapy have the potential to improve outcomes in high-risk T-ALL; however, cellular and genetic factors contributing to treatment resistance remain unknown. Previous bulk genomic studies in T-...

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Literature Corpus work: e91c31e1-6f4b-5829-8022-03ffda4cf960
DOI: 10.21203/rs.3.rs-3487715/v1

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