Article

An atlas of causal and mechanistic drivers of interpatient heterogeneity in glioma

2024-04-07

Abstract excerpt

<h4>ABSTRACT</h4> Grade IV glioma, formerly known as glioblastoma multiforme (GBM) is the most aggressive and lethal type of brain tumor, and its treatment remains challenging in part due to extensive interpatient heterogeneity in disease driving mechanisms and lack of prognostic and predictive biomarkers. Using mechanistic inference of node-edge relationship (MINER), we have analyzed multiomics profiles from 516...

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Literature Corpus work: d198b633-101a-5ec5-81f9-3f71ed720961
DOI: 10.1101/2024.04.05.24305380

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