Article

Multi-omics integrative analysis of the glioma microenvironment reveals IDH-dependent cellular communication and prognostic signatures

2026-07-23

Abstract excerpt

<title>Abstract</title> <p>Background Glioma is the most common primary malignant brain tumor. Isocitrate dehydrogenase (IDH) mutation status is a critical prognostic marker that fundamentally reshapes the tumor microenvironment (TME), particularly tumor-associated macrophages (TAMs). However, the IDH-dependent cellular communication landscape and its translational implications remain incompletely characterized,...

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Literature Corpus work: 0e807841-4964-5000-8321-35a8f620ab68
DOI: 10.21203/rs.3.rs-10343657/v1

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