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Article

Collagen 3D matrices as a model for the study of cell behavior in pulmonary fibrosis

16 Mar 2022

Abstract excerpt

Purpose: Idiopathic pulmonary fibrosis (IPF) is a complex progressive chronic lung disease where epithelial to mesenchymal interaction, extracellular matrix (ECM) contact, and pro-fibrotic cytokines dynamics take part in the development of the disease. The study of IPF in the widespread in vitro two-dimensional (2 D) culture fails to explain the interaction of cells with the changing environment that occurs in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35594338
DOI: 10.1080/01902148.2022.2067265

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