Article

Fibrotic human lung extracellular matrix as a disease-specific substrate for 3D <i>in-vitro</i> models of pulmonary fibrosis

2019-11-07

Abstract excerpt

<h4>ABSTRACT</h4> Idiopathic pulmonary fibrosis (IPF) is an irreversible and uniformly fatal lung disease marked by destruction and scarring of the lung parenchyma and progressive loss of respiratory function. IPF affects nearly 3 million people worldwide, and annual mortality in the US alone exceeds 40,000. Nintedanib and pirfenidone, the only drugs approved for the treatment of IPF, slow progression but do not...

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Literature Corpus work: 2cb3096c-381e-5223-8ca0-3b17182cec9a
DOI: 10.1101/833913

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