Article

Asymmetric stem cell division maintains genetic heterogeneity of tissue cells

2024-05-16

Abstract excerpt

<h4>ABSTRACT</h4> Within a given tissue, the stem cell niche provides the microenvironment for stem cells suitable for their self-renewal. Conceptually, the niche space constrains the size of a stem-cell pool, as the cells sharing the niche compete for its space. It has been suggested that either neutral-or non-neutral-competition of stem cells changes the clone dynamics of stem cells. Theoretically, if the rate...

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Literature Corpus work: d124268b-c844-5c00-9e0e-fb99a66fff55
DOI: 10.1101/2024.05.16.594576

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