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Article

Neutral competition of stem cells is skewed by proliferative changes downstream of Hh and Hpo.

The EMBO journal - 16 Oct 2014

Amoyel Marc, Simons Benjamin D, Bach Erika A

Abstract excerpt

Neutral competition, an emerging feature of stem cell homeostasis, posits that individual stem cells can be lost and replaced by their neighbors stochastically, resulting in chance dominance of a clone at the niche. A single stem cell with an oncogenic mutation could bias this process and clonally spread the mutation throughout the stem cell pool. The Drosophila testis provides an ideal system for testing this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25092766
DOI: 10.15252/embj.201387500
PMCID: PMC4253521

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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