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Article

(A)symmetric stem cell replication and cancer.

PLoS computational biology - 16 Mar 2007

Dingli David, Traulsen Arne, Michor Franziska, Michor Fransizka

Abstract excerpt

Most tissues in metazoans undergo continuous turnover due to cell death or epithelial shedding. Since cellular replication is associated with an inherent risk of mutagenesis, tissues are maintained by a small group of stem cells (SCs) that replicate slowly to maintain their own population and tha...

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Identifiers

PMID: 17367205
DOI: 10.1371/journal.pcbi.0030053
PMCID: PMC1828703

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17367205-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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