Article
[Mechanisms of asymmetric cell division: from model organisms to tumorigenesis].
Medecine sciences : M/S - 1 Mar 2010
Chartier Nicolas T, Hyenne Vincent, Labbé Jean-Claude
Abstract excerpt
Asymmetric cell division is the process by which a single cell gives rise to two different daughter cells. This process is important to generate cell diversity during the development of multicellular organisms, as well as for stem cell self-renewal in adults. Current knowledge on so-called cancer stem cells suggests that a loss of asymmetry during their division could lead to overproliferation and favour...
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