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Article

Stochastic stem cell models with mutation: A comparison of asymmetric and symmetric divisions.

Mathematical biosciences - 1 Feb 2021

Wu Zhijie, Wang Yuman, Wang Kun, Zhou Da

Abstract excerpt

In order to fulfill cell proliferation and differentiation through cellular hierarchy, stem cells can undergo either asymmetric or symmetric divisions. Recent studies pay special attention to the effect of different modes of stem cell division on the lifetime risk of cancer, and report that symmetric division is more beneficial to delay the onset of cancer. The fate uncertainty of symmetric division is considered...

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PMID: 33453222
DOI: 10.1016/j.mbs.2021.108541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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