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Age-related changes in the haematopoietic stem cell pool revealed via quantifying the balance of symmetric and asymmetric divisions.

2022-12-13

Abstract excerpt

<title>Abstract</title><p>Haematopoietic stem cells (HSCs) are somatic stem cells that continuously generate lifelong supply of blood cells through a balance of symmetric and asymmetric divisions. Recently, it is well established that the HSC pool increases with age. However, not much is known about the underlying cause for these observed changes. Here, using a novel method combining single-cell<italic>ex vivo</it...

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Literature Corpus work
a41cf9a8-7a6e-5ab2-b6c7-893964a885f8
DOI
10.21203/rs.3.rs-2300063/v1
Open publication

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Age-related changes in the haematopoietic stem cell pool revealed via quantifying the balance of symmetric and asymmetric divisions.DOI 10.21203/rs.3.rs-2300063/v1
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