Article
Regulation of self-renewal and differentiation in the Drosophila nervous system.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2008
Southall T D, Egger B, Gold K S, Brand A H
Abstract excerpt
Stem cells can divide symmetrically to generate two similar daughter cells and expand the stem cell pool or asymmetrically to self-renew and generate differentiating daughter cells. The proper balance between symmetric and asymmetric division is critical for the generation and subsequent repair of tissues. Furthermore, unregulated stem cell division has been shown to result in tumorous overgrowth. The Drosophila...
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