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Article

Symmetric vs. asymmetric stem cell divisions: an adaptation against cancer?

PloS one - 1 Jan 2013

Shahriyari Leili, Komarova Natalia L

Abstract excerpt

Traditionally, it has been held that a central characteristic of stem cells is their ability to divide asymmetrically. Recent advances in inducible genetic labeling provided ample evidence that symmetric stem cell divisions play an important role in adult mammalian homeostasis. It is well understood that the two types of cell divisions differ in terms of the stem cells' flexibility to expand when needed. On the...

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Identifiers

PMID: 24204602
DOI: 10.1371/journal.pone.0076195
PMCID: PMC3812169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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