Article

Structural basis for endotoxin neutralization and anti-inflammatory activity of thrombin-derived C-terminal peptides

2017-12-12

Abstract excerpt

Thrombin-derived C-terminal peptides (TCP) of about 2 kDa are present in wounds, where they exert anti-endotoxic functions. In an effort to elucidate the structural and molecular aspects of these functions, we here employ a combination of nuclear magnetic resonance spectroscopy (NMR), ellipsometry, fluorescence spectroscopy, circular dichroism (CD) measurements, and in silico multiscale modeling to define interac...

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Literature Corpus work: d0d16c09-a897-50f1-8b90-df289e8eead5
DOI: 10.1101/232876

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