Article

Acute induction of anomalous blood clotting by molecular amplification of highly substoichiometric levels of bacterial lipopolysaccharide (LPS)

2016-05-16

Abstract excerpt

<h4>ABSTRACT</h4> It is well known that a variety of inflammatory diseases are accompanied by hypercoagulability, and a number of more-or-less longer-term signalling pathways have been shown to be involved. In recent work, we have suggested a direct and primary role for bacterial lipopolysaccharide in this hypercoagulability, but it seems never to have been tested directly. Here we show that the addition of tiny...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 05aa980f-1139-545b-a96d-15ea0428a469
DOI: 10.1101/053538

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Acute induction of anomalous blood clotting by molecular amplification of highly substoichiometric levels of bacterial lipopolysaccharide (LPS)DOI 10.1101/053538Read

Substoichiometric molecular control and amplification of the initiation and nature of amyloid fibril formation: lessons from and for blood clottingSemantic proximity Read

Proteins behaving badly. Substoichiometric molecular control and amplification of the initiation and nature of amyloid fibril formation: lessons from and for blood clotting.Semantic proximity Read

Extracellular haemoglobin upregulates and binds to tissue factor on macrophages: implications for coagulation and oxidative stress.Semantic proximity Read

Inflammatory Triggers, Cell Death, Membrane Damage and Lipid Asymmetry That Shape Procoagulant Surfaces for Amyloidogenic MicroclottingSemantic proximity Read

The blood coagulation system as a molecular machine.Semantic proximity Read

Structural basis for endotoxin neutralization and anti-inflammatory activity of thrombin-derived C-terminal peptidesSemantic proximity Read

A Dormant Microbial Component in the Development of Pre-Eclampsia <sup>1</sup>Semantic proximity Read

Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory productsSemantic proximity Read

Soluble LIGHT (TNFSF14) activates endothelial cells, thereby priming the first vessel-occlusive events in acute sickle cell diseaseSemantic proximity Read

[Blood transfusion and inflammation as of yesterday, today and tomorrow].Semantic proximity Read

[The significance of circulating microparticles in physiology, inflammatory and thrombotic diseases].Semantic proximity Read

Fibrinogen Is at the Interface of Host Defense and Pathogen Virulence in Staphylococcus aureus InfectionSemantic proximity Read