Article

Novel insights into megakaryopoiesis, thrombopoiesis and acute coronary thrombosis : transcriptome profiling of the haematopoietic stem cell, megakaryocyte and platelet

2018-01-01

Abstract excerpt

The aim of this project was to investigate the transcriptome of human haematopoietic stem cells (HSCs), megakaryocytes and platelets to gain insights into steady state and accelerated thrombopoiesis that occurs in states of haemostatic demand and in thrombosis by applying these findings to the pathological setting of acute coronary thrombosis. To investigate transcriptional heterogeneity within the human HSC popul...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d0c9ce0f-4490-5d93-bc64-06518bff08d6
DOI: 10.17863/cam.30620

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Novel insights into megakaryopoiesis, thrombopoiesis and acute coronary thrombosis : transcriptome profiling of the haematopoietic stem cell, megakaryocyte and plateletDOI 10.17863/cam.30620Read

Single cell transcriptional characterization of human megakaryocyte lineage commitment and maturationSemantic proximity Read

The Analysis of the Human Megakaryocyte and Platelet Coding Transcriptome in Healthy and Diseased SubjectsSemantic proximity Read

The First Comprehensive Description of the Platelet Single Cell TranscriptomeSemantic proximity Read

The many faces of the megakaryocytes and their biological implicationsSemantic proximity Read

Transcriptional characterization of human megakaryocyte polyploidization and lineage commitmentSemantic proximity Read

Megakaryocyte and Platelet Transcriptomics for Discoveries in Human Health and DiseaseSemantic proximity Read

Characterization of Cellular Heterogeneity and an Immune Subpopulation of Human MegakaryocytesSemantic proximity Read

Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarctionSemantic proximity Read

Megakaryopoiesis and Platelet Biology: Roles of Transcription Factors and Emerging Clinical Implications.Semantic proximity Read

Deciphering transcriptome alterations in bone marrow hematopoiesis at single-cell resolution in immune thrombocytopeniaSemantic proximity Read

Single-cell analysis of megakaryopoiesis in peripheral CD34 <sup>+</sup> cells: insights into ETV6-related thrombocytopeniaSemantic proximity Read

The complex transcriptional landscape of the anucleate human plateletSemantic proximity Read