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Characterization of Cellular Heterogeneity and an Immune Subpopulation of Human Megakaryocytes

26 May 2021

Abstract excerpt

Abstract Megakaryocytes (MKs) and their progeny platelets function in a variety of biological processes including coagulation, hemostasis, inflammation, angiogenesis, and innate immunity. However, the divergent developmental and cellular landscape of adult MKs remains mysterious. Here, by deriving the single‐cell transcriptomic profiling of MKs from human adult bone marrow (BM), cellular heterogeneity within MKs...

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PMID: 34042332
DOI: 10.1002/advs.202100921

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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