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Megakaryocyte and Platelet Transcriptomics for Discoveries in Human Health and Disease

16 Apr 2020

Abstract excerpt

Anucleate platelets, long viewed as merely cell fragments with a limited repertoire of rapid-acting hemostatic functions, are now recognized to have a complex and dynamic transcriptome mirroring that of many nucleated cells. The field of megakaryocyte and platelet transcriptomics has been rapidly growing, particularly with the advent of newer technologies such as next-generation RNA-sequencing. Studies...

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PMID: 32295424
DOI: 10.1161/atvbaha.119.313280

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