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Article

The complex transcriptional landscape of the anucleate human platelet

1 Jan 2013

Abstract excerpt

BACKGROUND: Human blood platelets are essential to maintaining normal hemostasis, and platelet dysfunction often causes bleeding or thrombosis. Estimates of genome-wide platelet RNA expression using microarrays have provided insights to the platelet transcriptome but were limited by the number of known transcripts. The goal of this effort was to deep-sequence RNA from leukocyte-depleted platelets to capture the...

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PMID: 23323973
DOI: 10.1186/1471-2164-14-1

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