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Article

Megakaryopoiesis and Platelet Biology: Roles of Transcription Factors and Emerging Clinical Implications.

International journal of molecular sciences - 5 Sept 2021

Noh Ji-Yoon

Abstract excerpt

Platelets play a critical role in hemostasis and thrombus formation. Platelets are small, anucleate, and short-lived blood cells that are produced by the large, polyploid, and hematopoietic stem cell (HSC)-derived megakaryocytes in bone marrow. Approximately 3000 platelets are released from one megakaryocyte, and thus, it is important to understand the physiologically relevant mechanism of development of mature...

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Identifiers

PMID: 34502524
DOI: 10.3390/ijms22179615
PMCID: PMC8431765

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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