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Article

The many faces of the megakaryocytes and their biological implications

1 Nov 2023

Abstract excerpt

PURPOSE OF REVIEW: Single-cell RNA sequencing studies have revealed transcriptional heterogeneity within the megakaryocytic lineage and the identified unique subsets. In this review, we discuss the functional and phenotypic plasticity of these subpopulations as well as the impacts on health and disease. RECENT FINDINGS: Megakaryocytes (MKs) can be transcriptionally categorized into platelet generating, niche...

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PMID: 37910197
DOI: 10.1097/moh.0000000000000793

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