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IRF7 from the black flying fox induces a STAT1-independent ISG response in unstimulated cell lines that protects against diverse RNA viruses

2024-05-05

Abstract excerpt

Bats are considered unique in their ability to harbor large numbers of viruses and serve as reservoirs for zoonotic viruses that have the potential to spill over into humans. However, these animals appear relatively resistant to the pathogenic effects of many viruses. Mounting evidence suggests that bats may tolerate viral infections due to unique immune features. These include evolutionary innovations in inflamma...

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Identifiers and source

Literature Corpus work
9dcb5e8d-d871-57ca-b193-3b45cd814a7f
DOI
10.1101/2024.05.02.592239
Open publication

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IRF7 from the black flying fox induces a STAT1-independent ISG response in unstimulated cell lines that protects against diverse RNA virusesDOI 10.1101/2024.05.02.592239
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