Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Beyond Good and Evil: Molecular Mechanisms of Type I and III IFN Functions

1 Jan 2022

Abstract excerpt

IFNs are comprised of three families of cytokines that confer protection against pathogen infection and uncontrolled cellular proliferation. The broad role IFNs play in innate and adaptive immune regulation has placed them under heavy scrutiny to position them as "friend" or "foe" across pathologies. Genetic lesions in genes involving IFN synthesis and signaling underscore the disparate outcomes of aberrant IFN...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Immune Cell Function and Interaction
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35017214
DOI: 10.4049/jimmunol.2100707

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Beyond Good and Evil: Molecular Mechanisms of Type I and III IFN FunctionsPMID 35017214Read ↗

Type I interferons in health and disease: molecular aspects and clinical implicationsSemantic proximity Read ↗

[Review] The Landscape of Interferons in Health and DiseaseSemantic proximity Read ↗

Protective Potentials of Type III Interferons in COVID-19 Patients: Lessons from Differential Properties of Type I- and III InterferonsSemantic proximity Read ↗

Interferon Lambda Genetics and Biology in Regulation of Viral ControlSemantic proximity Read ↗

Interferon-Stimulated Genes: What Do They All Do?Semantic proximity Read ↗

Type III Interferons: Emerging Roles in AutoimmunitySemantic proximity Read ↗

Type I IFN family members: similarity, differences and interaction.Semantic proximity Read ↗

Regulating IRFs in IFN Driven DiseaseSemantic proximity Read ↗

Interferons in Autoimmune and Inflammatory Diseases: Regulation and RolesSemantic proximity Read ↗

TYPE I INTERFERONS (α/β) IN IMMUNITY AND AUTOIMMUNITYSemantic proximity Read ↗

Interference without interferon: interferon-independent induction of interferon-stimulated genes and its role in cellular innate immunitySemantic proximity Read ↗

The Yin and Yang of Type I IFNs in Cancer Promotion and Immune ActivationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.