Article

Chromothripsis-like patterns are recurring but heterogeneously distributed features in a survey of 22,347 cancer genome screens

2014-01-13

Abstract excerpt

<h4>Background</h4> Chromothripsis is a recently discovered phenomenon of genomic rearrangement, possibly arising during a single genome-shattering event. This could provide an alternative paradigm in cancer development, replacing the gradual accumulation of genomic changes with a “one-off” catastrophic event. However, the term has been used with varying operational definitions, with the minimal consensus being a...

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Literature Corpus work: d04d9f76-121e-51c5-9890-b395797e5631
DOI: 10.1101/001776

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