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Article

Chromothripsis-like patterns are recurring but heterogeneously distributed features in a survey of 22,347 cancer genome screens.

BMC genomics - 29 Jan 2014

Cai Haoyang, Kumar Nitin, Bagheri Homayoun C, von Mering Christian, Robinson Mark D, Baudis Michael

Abstract excerpt

BACKGROUND: Chromothripsis is a recently discovered phenomenon of genomic rearrangement, possibly arising during a single genome-shattering event. This could provide an alternative paradigm in cancer development, replacing the gradual accumulation of genomic changes with a "one-off" catastrophic event. However, the term has been used with varying operational definitions, with the minimal consensus being a large...

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Identifiers

PMID: 24476156
DOI: 10.1186/1471-2164-15-82
PMCID: PMC3909908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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