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Article

A survey of cancer genome signatures identifies genes connected to distinct chromosomal instability phenotypes.

The pharmacogenomics journal - 1 Jun 2021

Shafat Manar S, Rufaie Eamaan S, Watkins Johnathan

Abstract excerpt

Certain breast and ovarian cancers are characterised by high levels of chromosomal instability. We established a suite of eleven SNP array-based signatures of various forms of chromosomal instability. To understand what biological mechanisms might underpin these signatures, we generated and assembled genetic-feature data including allele-specific expression, fusion genes, gene expression, methylation, somatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33731882
DOI: 10.1038/s41397-021-00217-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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