Article

Validation of Enhancer Regions in Primary Human Neural Progenitor Cells using Capture STARR-seq

2024-03-18

Abstract excerpt

Genome-wide association studies (GWAS) and expression analyses implicate noncoding regulatory regions as harboring risk factors for psychiatric disease, but functional characterization of these regions remains limited. We performed capture STARR-sequencing of over 78,000 candidate regions to identify active enhancers in primary human neural progenitor cells (phNPCs). We selected candidate regions by integrating da...

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Literature Corpus work: d02b7bc9-cba4-590f-9c0c-d5ecf3f34cb8
DOI: 10.1101/2024.03.14.585066

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