Article

The role of Med15 sequence features in transcription factor interactions

2024-05-05

Abstract excerpt

Med15 is a general transcriptional regulator and subunit within the tail module of the RNA Pol II Mediator complex. The S. cerevisiae Med15 protein has a well-structured N-terminal KIX domain, three Activator Binding Domains (ABDs), several naturally variable polyglutamine (poly-Q) tracts (Q1, Q2, Q3) embedded in an intrinsically disordered central region, and a C-terminal Mediator Association Domain (MAD). We in...

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Literature Corpus work: cfb9e4c0-de98-5dc7-b456-10cfac330e8b
DOI: 10.1101/2024.05.04.592524

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