Article
The Polymorphic PolyQ Tail Protein of the Mediator Complex, Med15, Regulates the Variable Response to Diverse Stresses.
International journal of molecular sciences - 10 Mar 2020
Gallagher Jennifer E G, Ser Suk Lan, Ayers Michael C, Nassif Casey, Pupo Amaury
Abstract excerpt
The Mediator is composed of multiple subunits conserved from yeast to humans and plays a central role in transcription. The tail components are not required for basal transcription but are required for responses to different stresses. While some stresses are familiar, such as heat, desiccation, and starvation, others are exotic, yet yeast can elicit a successful stress response. 4-Methylcyclohexane methanol...
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