Article
The structural and functional role of Med5 in the yeast Mediator tail module.
The Journal of biological chemistry - 16 Dec 2005
Béve Jenny, Hu Guo-Zhen, Myers Lawrence C, Balciunas Darius, Werngren Olivera, Hultenby Kjell, Wibom Rolf, Ronne Hans, Gustafsson Claes M
Abstract excerpt
Med5 (Nut1) is identified here as a component of the Mediator tail region. Med5 is positioned peripherally to Med16 (Sin4) together with the three members of the putative Gal11 module, Med15 (Gal11), Med2, and Med3 (Pgd1). The biochemical analysis receives support from genetic interactions between med5delta and med15delta deletions. The med5delta and med16delta deletion strains share many phenotypes, including...
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